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Q: Is there a “natural” replacement for Premarin?

by Dr. Barb DePree MD

In a sense, the most “natural” replacement for lost estrogen is estrogen, which is a prescription product (like Premarin or Estrace vaginal cream, Estring, Vagifem, or the non-estrogen Osphena).

You asked. Dr. Barb answered.If, for a number of reasons, you prefer not to take that path, the next-best option is to maintain vaginal tissues by using a moisturizer regularly, two to three times a week. Moisturizers are designed to bring more moisture--no surprise--into the vagina to prevent the progressive dryness that occurs in menopause with the absence of estrogen.

Both Emerita and Prevaleaf Oasis are natural vaginal moisturizers.

Shop Comfort and Vaginal Health Products

One more option might be an oral nutritional supplement, Stronvivo, which some research shows improves vaginal moisture. It does this by improving blood flow, and that circulation also supports tissue health.




  • Remi, Hair loss can be a side effect of both menopause and hormone replacement. There are alternatives to Premarin including hormonal and non-hormonal options. If you would like to continue with a product containing estrogen, you will need to discuss this with your provider. If you would like to stay away from hormones, using a moisturizer will help maintain vaginal tissue.

    Dr Barb on

  • Noticed significant hair loss with Premarin. What alternative do I have

    Remi on

  • Jill, Premarin is safe to use following treatment of skin cancer.

    Dr Barb on

  • Karen, yes. Premarin (both oral and vaginal) would likely help reduce the occurrence of bladder infections.

    Dr Barb on

  • I keep a bladder infection and my doctor thinks premarin will help. Could you give me your opinion on that?

    Karen on

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