Vagifem is a vaginal estrogen, applied locally. It is safe for someone with your medical history, posing no risk of thrombosis. Only oral estrogen, which enters the system rather than being applied directly to vaginal tissues, poses some risk of thrombosis or clotting. You might find an earlier blog post about localized estrogen
helpful; in it I described the benefits, forms, and cautions for using vaginal estrogen.
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