You say you’re considering removal of ovaries because of a BRCA2 gene mutation; you’ve already had prophylactic mastectomies. The good news is yes, a woman can still orgasm after removal of the ovaries. For a few women, the removal of the ovaries can impact sex by lowering libido and making it harder to arouse and orgasm, but the majority have no significant impact sexually. A woman’s age makes a difference as well: A 35-year-old will likely have a more notable loss of function than a 55-year-old.
And hormones can be added back. Even with the BRCA2 gene mutation present, there is no contraindication to using hormone therapy. Hormone therapy may include estrogen and/or testosterone to address sexual concerns. These are not always the complete answer for every woman’s sexual concern, but they can be very helpful for some. (Unfortunately testosterone is not FDA-approved for women, so its use is “off label” and not all providers are comfortable prescribing it.)
Removing ovaries seems like the clear right choice with your knowledge of having a BRCA2 mutation. Best wishes for your continued health!