Estrogen--and vaginal moisturizers--generally lower the pH level, making it a more healthy environment. The vagina is typically slightly acidic, like tomatoes or wine. The loss of estrogen with menopause can throw off our pH levels, reducing circulation and lubrication. Being able to generate enough moisture is part of what allows our vaginas to reregulate pH level after intercourse, when semen, which is more alkaline, is temporarily disruptive.
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Estring, a vaginal ring, is one method for delivering localized hormones—in this case estradiol. The ring itself includes silicone polymers, so I recommend to my patients that they use a water-based or hybrid lubricant. Among water-based lubricants, Yes and Aloe Cadabra are often ordered. Sliquid Organics Silk is popular among post-menopausal women; as a hybrid lubricant, it has the benefits of water-based but is more long lasting, like silicone-based.
Silicone-based lubricants aren't recommended for use with products made from
silicone—like the Estring and some vibrators or other sex toys—because the formula may cause disintegration of the surface.